国家自然科学奖二等奖
项目名称：双面对称核苷的设计合成与抗口腔黏膜病相关病毒作用机制研究
提名者：中华口腔医学会
代表性论文（专著）目录：
- Haozhe Yang, Meiying Pan, Dawei Jiang, Yang He*. Synthesis of Janus type nucleoside analogues and their preliminary bioactivity. Organic & Biomolecular Chemistry 2011, 9(5): 1516-1522.
- Hang Zhao#, Xiurong Guo#, Shiling He#, Xin Zeng, Xinglong Zhou, Chaoliang Zhang, Jing Hu, Xiaohua Wu, Zhihua Xing, Liangyin Chu, Yang He*, Qianming Chen*. Complex self-assembly of pyrimido [4, 5-d] pyrimidine nucleoside supramolecular structures. Nature Communications 2014, 5(1): 3108.
- Hang Zhao#, Hui Feng#, Dongjuan Liu#, Jiang Liu, Ning Ji, Fangman Chen, Xiaobo Luo, Yu Zhou, Hongxia Dan, Jing Li, Congkui Sun, Xiaojie Meng, Ming Zhou, Hansuo Yang, Liangyin Chu, Lu Jiang*, Yang He*, Qianming Chen*. Self-assembling monomeric nucleoside molecular nanoparticles loaded with 5-FU enhancing therapeutic efficacy against oral cancer. ACS nano 2015, 9(10): 9638-9651.
- Hang Zhao, Wen Huang, Xiaohua Wu, Zhihua Xing, Yang He*, Qianming Chen*. Different superstructures formed by Janus-type nucleosides. Chemical Communications 2012, 48(49): 6097-6099.
- Jiang Liu#, Hang Zhao#, Xinglong Zhou, Yang He*, Qianming Chen*. Antiviral activities of Janus-type nucleosides and their related oxime-intermediates. Bioorganic & Medicinal Chemistry 2019, 27(12): 2332-2339.
主要完成人（完成单位）：陈谦明（四川大学）、何杨（四川大学）、赵行（四川大学）、曾昕（四川大学）、刘江（四川大学）
